Chengtie Wu, Ph.D.
Professor, Shanghai Institute of Ceramics,
Chinese Academy of Sciences
chengtiewu@mail.sic.ac.cn
Biography:Prof. Chengtie Wu, Deputy Director, Shanghai Institute of Ceramics, Chinese Academy of Sciences (SIC, CAS). He completed his Ph.D in 2006, and then he worked in the University of Sydney, Dresden University of Technology, Germany and Queensland University of Technology where he received Vice-Chancellor Research Fellow, APDI Fellow and Alexander von Humboldt Fellow. In 2012, Dr Wu has been recruited to work in SIC, CAS, as One-Hundred Talent Program of Chinese Academy of Sciences. Then he was awarded Recruitment Program of Global Young Experts of China (Qingnian Qianren Jihua), Shanghai Pujiang Talent Program and Shanghai Outstanding Academic Leaders. In 2019, Prof. Wu was awarded National Special Support Program for High-level Personnel Recruitment (Wanren Jihua). Prof Wu’s research focuses on 3D printing of bioactive inorganic materials for bone tissue engineering. Up to now, Prof Wu has published more than 220 SCI peer-review journal papers, including Mater Today, ACS Nano, Nano Lett, Biomaterials, Adv Funct Mater, Adv Science, Chem Mater, etc. The papers have been cited more than 8500 times, H Index 56 via SCI, Web of Science. Prof Wu has been awarded 29 patents, in which 3 of them have been transferred to companies. Prof Wu was awarded the Journal of Materials Chemistry Lectureship in 2015, Young Scientists of Chinese Biomaterials Society in 2016, Outstanding Young Scientists of Chinese Ceramics Society in 2018”, and The First Prize in Science and Technology of Chinese Society of Biomaterials in 2019. He is now the Associate editors for “Applied Materials Today”, and “Journal of Inorganic Materials”, as well as the editorial board member of “Acta Biomaterialia”.
Topic title：3D Printing of Biomimetic Bioactive Materials
Abstract：For therapy and regeneration of bone defects resulting from malignant bone disease, it is of great importance to develop multifunctional biomaterials for bone therapy and regeneration. Conventional biomaterials always lack multifunctional properties, limiting their application for treating and repairing bone disease (e.g. bone tumors)-initiated defects. How to design and prepare bioscaffolds with favorable microenvironments for disease therapy and tissue regeneration is one of interesting topics in the fields of biomaterials and tissue engineering. We developed several strategies, including harnessing nutrient elements, biomimetic structure and functional interface as well as thermo-therapy to construct multifunctional scaffolds by 3D-Pringting method for therapy and regeneration of bone tissues. It is interesting to find that both nutrient elements and biomimetic structure of the printed bioscaffolds have important effect on the stimulation of osteogenesis and angiogenesis of stem cells, and thermotherapy plays an important role to treating bone tumors. Therefore, we put forward new concept that 3D-Printed bioscaffolds combined bone therapy and regeneration could be a new direction of bone tissue engineering.
REFERENCES
1. Xiaocheng Wang, Bing Ma, Jianmin Xue, JinFu Wu, Jiang Chang, Chengtie Wu*. Defective black nano-titania/thermogels for cutaneous tumor-induced therapy and healing. Nano Letters 19 (3):2138–2147 (2019)
2. Cuijun Deng, Rongcai Lin, MengZhang, Chen Qin, Qingqiang Yao*, Liming Wang, Jiang Chang, Chengtie Wu*. Micro/nanometer-structured scaffolds for regeneration of both cartilage and subchondral Bone. Advanced Functional Materials 29;1806068:1-15 (2019)
3. Qingqing Yu, Yiming Han, Tian Tian, Quan Zhou, Zhengfang Yi, Jiang Chang, Chengtie Wu.* Chinese sesame stick-inspired nano-fibrous scaffolds for tumor therapy and skin tissue reconstruction. Biomaterials 194:25-35 (2019)
4. Jianmin Xue, Chun Feng, Lunguo Xia, Dong Zhai, Bing Ma, Xiaocheng Wang, Bing Fang, Jiang Chang, Chengtie Wu*. Assembly preparation of multilayered biomaterials with high mechanical strength and bone-forming bioactivity. Chemistry of Materials 30(14):4646–4657 (2018)
5. Chun Feng, Wenjie Zhang, Cuijun Deng, Guanglong Li, Jiang Chang, Zhiyuan Zhang, Xinquan Jiang*, Chengtie Wu*. 3D Printing oflotus root-like biomimetic materials for cell Delivery and tissue regeneration. Advanced Science 4:1700401 (2017)
6. Hongshi Ma, Chuan Jiang, Dong Zhai, Yongxiang Luo, Yu Chen, Fang Lv, Zhengfang Yi, Yuan Deng, Jinwu Wang, Jiang Chang,* Chengtie Wu*. A bifunctional biomaterial with photothermal effect for tumor therapy and bone regeneration. Advanced Functional Materials 26:1197-1208 (2016)
